Anionic Liposomes and Lipid Nanoparticles
Anionic liposomes are structures that are made of negatively charged lipids and are vastly utilized in gene delivery and transfection applications.
|DOPS:DOPC Liposomes (1-2)|
|DOPS Liposomes (3)|
1) Forssen, Eric A., and Z. A. Tökès. "Use of anionic liposomes for the reduction of chronic doxorubicin-induced cardiotoxicity." Proceedings of the National Academy of Sciences 78.3 (1981): 1873-1877.
2) Patil, Siddhesh D., David G. Rhodes, and Diane J. Burgess. "Anionic liposomal delivery system for DNA transfection." The AAPS journal 6.4 (2004): 13-22.
3) Tarahovsky, Yury S., Rumiana Koynova, and Robert C. MacDonald. "DNA release from lipoplexes by anionic lipids: correlation with lipid mesomorphism, interfacial curvature, and membrane fusion." Biophysical journal 87.2 (2004): 1054-1064.