Learn About Latest High Impact Developments in Industry and Academia

Taylor Dispersion Analysis to support lipid-nanoparticle formulations for mRNA vaccines

Lipid nanoparticles (LNPs) are currently the most advanced non-viral clinically approved messenger ribonucleic acid (mRNA) delivery systems....

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Payload distribution and capacity of mRNA lipid nanoparticles

Lipid nanoparticles (LNPs) are effective vehicles to deliver mRNA vaccines and therapeutics. It has been challenging to assess mRNA packaging characteristics.....

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Circular RNA: An emerging frontier in RNA therapeutic targets, RNA therapeutics, and mRNA vaccines

Circular RNAs (circRNA) is a class of natural (biogenic) or synthetic closed RNA without 5′ or 3′ ends......

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Full encapsulation of oncolytic virus using hybrid erythroctye-liposome membranes for augmented anti-refractory tumor effectiveness

Intravenous delivery of oncolytic virus (OVs) is promising in cancer treatment.

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Innate immune mechanisms of mRNA vaccines

The lipid nanoparticle (LNP)-encapsulated, nucleoside-modified mRNA platform has been used to generate safe and effective vaccines in record time against COVID-19.

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Self-amplifying RNA vaccine protects mice against lethal Ebola virus infection

Emerging and re-emerging viruses, such as Zaire Ebola virus (EBOV), pose a global threat and require immediate countermeasures....

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CRISPR cancer trial success paves the way for personalized treatments

‘Most complicated therapy ever’ tailors bespoke, genome-edited immune cells to attack tumours.

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Broadening the Horizons of RNA Delivery Strategies in Cancer Therapy

RNA-based therapy is a promising and innovative strategy for cancer treatment. However....

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KRAS-Targeted Therapy Doubles as Component of Immunotherapy

Some of the deadliest cancers have mutations in a gene called KRAS. The recent development of drugs ....

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Bio-macromolecular design roadmap towards tough bioadhesives 

Emerging sutureless wound-closure techniques have led to paradigm shifts in wound management. 

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mRNA nanomedicine: Design and recent applications

The rational design and application of mRNA-based medicine have recently yielded some key successes ....

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Lipid Nanoparticle (LNP) Chemistry Can Endow Unique In Vivo RNA Delivery

Within the field of lipid nanoparticles (LNPs) for RNA delivery, the focus has been mainly placed on organ level delivery....

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Leveraging Biological Buffers for Efficient Messenger RNA Delivery via Lipid Nanoparticles

Lipid nanoparticles containing messenger RNA (mRNA-LNPs) have launched to the forefront of nonviral delivery systems with their realized potential during the COVID-19 pandemic. 

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mRNA nanomedicine: Design and recent applications

The rational design and application of mRNA-based medicine have recently yielded some key successes ....

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Lipid Nanoparticle (LNP) Chemistry Can Endow Unique In Vivo RNA Delivery

Within the field of lipid nanoparticles (LNPs) for RNA delivery, the focus has been mainly placed on organ level delivery....

Learn More