Lipid Nanoparticles for Gene Delivery

T&T Scientific’s ProFECT™ Transfection Kits are a proprietary and patent-protected lipid-based transfection system designed for safe and effective nucleic acid delivery in a broad range of cell types with high viability and low lipid-associated toxicity. ProFECT™, a natural lipid composition comprised of non-cationic phospholipid and sterol components, is modified with functional amino acids for highly efficient encapsulation of DNA, mRNA, siRNA and enhanced intracellular delivery. 

This easy-to-use lipid formulation is intended for preclinical in vitro studies aimed at translational development of DNA, mRNA, and siRNA therapeutics.

 ProFECT(siRNA) Plus (1)
 ProFECT(mRNA) Plus (1)

 ProFECT(DNA) Plus (1)



1) Fisher, R. K., Mattern-Schain, S. I., Best, M. D., Kirkpatrick, S. S., Freeman, M. B., Grandas, O. H., & Mountain, D. J. (2017). Improving the efficacy of liposome-mediated vascular gene therapy via lipid surface modifications. Journal of Surgical Research, 219, 136-144.