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Designing, Functionalizing, Optimize, and Improvement on Lipid or Polymer Based Nanoparticles
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Nucleic Acids (mRNA, siRNA, DNA) and Olegonucleotides
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Antibody
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Peptides
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Proteins
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Small and Large Molecules
Preclinical Drug Delivery System Formulation Discovery and Optimization
Preclinical
Formulation Discovery and Optimization
Preclinical Development
(Scale Up, Methods, Processes)
Clinical Phase
I/II/III
Commercial
Fill and Finish
Design and Optimization of Drug Delivery Systems
Analytical Characterizations and Methods Development
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Size by Dynamic Light Scattering
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Charge - Zeta Potential
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Purity by HPLC/ELSD, and UV
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UV-Vis spectroscopy
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Residual Solvent by GC-FID
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Identity Testing and Assays by HPLC-MS
Sample Preparation for All Preclinical Studies
Sample Preparation: Small to large scale sample preparation of LNP with or without your cargo, including
LNP
- Nucleic Acids (mRNA, siRNA, DNA)
- Antibody
- Peptides
- Proteins
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Small and Large Molecules
Scalable Manufacturing Process Development
We have all processes that are needed to prepare your LNP therapeutics or vaccine samples including:
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Solvent and Ethanol Injection Microfluidics
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Thin-Film Hydration
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Extrusion
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Microfluidizer Homogenization
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Lyophilization
Studies Plan and Executions
STUDIES, EXPERIMENTATIONS, ANALYTICAL METHODS
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Our formulation department will help you plan, perform, and reporting such as:
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Stability Studies
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Size,
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Charge,
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UV-Vis,
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Purity and Concentrations (HPLC/GC-FID/GC-MS, and LC-MS)