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MOPC (17:0,18:1 PC): 1-Margaroyl-2-oleoyl-sn-glycero-3-phosphocholine
Phosphatidylcholine (PC) is generally the most abundant lipid in animal cell membranes providing a structural framework. PC is more common in the outer leaflet where it functions as part of the permeability barrier. PC is also the primary substrate of Phospholipase D enzymes which produce the signaling lipids - phosphatidic acid and lysophosphatidic acid.
|Solubility||CHCl3, CH3OH > 1 mg/mL|
Storage: 1-Heptadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine (17:0,18:1 PC) is stable for at least one year when stored as a solid, protected from moisture, and light at -20 °C. Reconstitute with methanol and dilute with water or neutral pH buffered salt solutions i.e. PBS, TBS, etc. Material should be stored in glass containers to prevent loss due to adsorption to the vessel surface. Storage in basic (pH > 9) or acidic (pH < 4) buffers will result in slow decomposition of the product. After reconstitution, solutions of 17:0,18:1 PC should be flash frozen in liquid nitrogen and stored at -20 °C between uses. 17:0,18:1 P C is stable for at least three months when handled in this way. Repeated freeze/thaw cycles do not affect 17:0,18:1 PC. Do not store reconstituted lipid at 4°C for mo re than 2-3 days.
Field of Interest: Phosphatidylcholine (PC) is generally the most abundant lipid in animal cell membranes providing structural framework. PC is more common in the outer leaflet where it functions as part of the permeability barrier. PC is also the primary substrate of Phospholipase D enzymes which produce the signaling lipids – phosphatidic acid and lysophosphatidic acid.
Hazardous Properties and Cautions: No hazardous or toxic properties are known for this substance. Biotin-Labeled Phosphatidylcholine is not listed as a hazardous waste or as a Toxic Chemical subject to release reporting under the Emergency Planning and Community Right-to-Know Act. For solutions containing methanol or other solvents, see MSDS for Phosphoinositides in Solution available on request. 17:0,18:1 PC is not listed on the Chemical Inventory of the Toxic Substance Control Act, and is manufactured and shipped only in small quantities, intended for research and development in a laboratory utilizing prudent procedures for handling chemicals of unknown toxicity, under the supervision of persons technically qualified to evaluate potential risks and authorized to enforce appropriate health and safety measures. As with all research chemicals, precautions should be taken to avoid unnecessary exposures or risks.
Warranty and Disclaimer: T&T warrants the product conforms to the specifications stated herein. In the event of nonconformity, T&T will replace products or refund purchase price, at its sole option, and we shall not be responsible for any other loss or damage, whether known or foreseeable to T&T. No other warranties apply, express or implied, including but not limited to warranty of fitness for any purpose or implied warranty of merchantability. Purchaser is solely responsible for all consequences of its use of the product and T&T assumes no responsibility therefore, including success of purchaser's research and development, or health or safety of any uses of the product.
Notice: T&T Scientific products are sold for research and development purposes only and are not for diagnostic use or to be incorporated into products for resale without written permission form T&T Scientific. Materials in this publication, as well as applications and methods and use, may be covered by one or more U.S. or foreign patents or patents pending.